Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 4.889


Transcription factors associated with FOS_FOS{B,L1}_JUN{B,D}.p2:

Gene SymbolEntrez IDGene Name
FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
FOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 8061 FOS-like antigen 1
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSchr14_+_74815233-0.496.3e-02Click!
FOSL1chr11_-_654244360.477.6e-02Click!
FOSBchr19_+_50663089-0.401.4e-01Click!
JUNDchr19_-_182534130.155.8e-01Click!
JUNBchr19_+_127632850.136.5e-01Click!


Activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2.

activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2


Sorted Z-values histogram for motif FOS_FOS{B,L1}_JUN{B,D}.p2

Sorted Z-values for motif FOS_FOS{B,L1}_JUN{B,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOS_FOS{B,L1}_JUN{B,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_59593591 19.374 NM_003784
 SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr17_-_37022465 18.628 NM_005557
 KRT16
keratin 16
chr3_+_11153778 17.948 NM_001098213
 HRH1
histamine receptor H1
chr9_-_90456824 16.721 NM_001100111
 LOC286238
hypothetical protein LOC286238
chr5_+_150000394 15.891 NM_001109974
NM_007286
 SYNPO

synaptopodin

chr21_+_29439768 15.106 C21orf7
chromosome 21 open reading frame 7
chr13_-_35327798 14.862 NM_001195415
NM_001195416
NM_001195430
 DCLK1


doublecortin-like kinase 1


chr1_+_221955876 14.856 NM_001146068
 CAPN2
calpain 2, (m/II) large subunit
chr8_+_22900863 14.800 NM_001160036
 RHOBTB2
Rho-related BTB domain containing 2
chr6_+_47774247 14.267 NM_153838
 GPR115
G protein-coupled receptor 115
chr11_-_102219450 14.162 NM_002422
 MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_-_68369322 13.410 NM_152439
 BEST3
bestrophin 3
chr7_+_72883128 13.317 NM_001305
 CLDN4
claudin 4
chr1_+_17719405 13.240 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_-_36469869 13.172 NM_001165252
 LOC730755
keratin associated protein 2-4-like
chr17_+_21131940 13.082 NM_002756
 MAP2K3
mitogen-activated protein kinase kinase 3
chr18_+_19947314 12.967 TTC39C
tetratricopeptide repeat domain 39C
chr13_+_77007809 12.358 NM_001160706
NM_003843
NM_144777
 SCEL


sciellin


chr3_-_11585264 12.226 NM_001128221
 VGLL4
vestigial like 4 (Drosophila)
chr5_+_140848905 12.181 NM_018929
NM_032407
 PCDHGC5

protocadherin gamma subfamily C, 5


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.65 1.83e-03 GO:0009888 tissue development
1.58 1.55e-02 GO:0009611 response to wounding
1.38 1.29e-02 GO:0048513 organ development
1.31 5.15e-03 GO:0048731 system development
1.30 2.83e-03 GO:0048856 anatomical structure development

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
5.10 3.05e-02 GO:0001533 cornified envelope
2.49 3.31e-02 GO:0044449 contractile fiber part
1.84 3.45e-02 GO:0005578 proteinaceous extracellular matrix
1.48 8.61e-03 GO:0044421 extracellular region part
1.37 1.88e-02 GO:0005856 cytoskeleton
1.36 1.37e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.89 1.45e-02 GO:0004867 serine-type endopeptidase inhibitor activity
2.55 2.54e-03 GO:0004866 endopeptidase inhibitor activity
2.50 2.50e-03 GO:0030414 peptidase inhibitor activity
2.45 5.65e-03 GO:0061135 endopeptidase regulator activity
2.17 3.11e-02 GO:0061134 peptidase regulator activity
1.85 1.53e-02 GO:0004175 endopeptidase activity
1.14 1.85e-02 GO:0005515 protein binding